Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
OVCA1 Antibody (6E93) is a high quality monoclonal OVCA1 antibody (also designated OVCA1 antibody) suitable for the detection of the OVCA1 protein of human origin. OVCA1 Antibody (6E93) is available as the non-conjugated anti-OVCA1 antibody. OVCA1 (Ovarian cancer-associated gene 1 protein) is a nuclear protein that belongs to the DPH1/DPH2 family (DPH1 subfamily). Diphthamide is a modified histidine amino acid that is created by a posttranslational modification of eukaryotic elongation factor 2 (EF-2). Diphthamide is the target for ADP-ribosylation by diphtheria toxin, which renders the elongation factor inactive. The diphthamide modification is conserved in all eukaryotes and archaebacteria and is formed by the actions of five proteins, Dph1-5, and an amidating enzyme. OVCA1 (Dph-1) is required for the first step in the synthesis of diphthamide. The chromosomal region that contains OVCA1, 17p13.3, is frequently deleted in human ovarian carcinoma, suggesting this 15 kb region of deletion may contain a tumor suppressor gene. OVCA1 acts as a tumor suppressor in lung and breast cancers and when overexpressed will suppress colony formation and growth rate of ovarian cancer cells. OVCA1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, mammary gland, colon, small intestine, testis and ovary.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using OVCA1 (6E93): sc-101248 for immunofluorescence, what dilution of this antibody should I use?
Asked by: Cweed
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: