Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). The NUP98 gene encodes precursor proteins that generate two nucleoplasmically oriented nucleoporins, Nup98 and Nup96. The O-linked glycoprotein, Nup98 is a component of the nuclear pore complex. Nup98 is essential for gastrulation, a developmental stage that is associated with rapid cell proliferation, but dispensable for basal cell growth. Nup98 plays a role in RNA export from the nucleus and it appears to be an essential component of multiple RNA export pathways. Nup98 is a member of the GLFG nucleoporin family. The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for Nup98 and class I homeoprotein HoxA9. Nup98-HoxA9 fusion protein may promote leukemogenesis through inhibiting of HoxA9-mediated terminal differentiation and/or aberrant nucleocytoplasmic transport.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.