Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Nucleobindin, also designated Nuc or Calnuc, is a secreted protein that promotes production of DNA-specific antibodies in lupus-prone MRL/lpr mice. Nucleobindin contains a signal peptide, two EF-hand motifs, acidic and basic regions and a leucine-zipper motif. Nucleobindin has two calcium-binding domains and is the major Golgi Ca2+ binding protein. The leucine zipper structure and the basic amino acid-rich region are responsible for DNA binding. Nucleobindin preferentially associates with membranes of polarized cells. Nucleobindin is found in both the cytosol and the membrane and is localized to cis-Golgi cisternae and the cis-Golgi network (CGN). Nucleobindin is involved in autoimmunity, apoptosis and calcium homeostasis in the bone matrix.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100793: nucleobindin (R-Y2) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Dr Ninau Qelp
Thank you for your question. Yes, sc-100793: nucleobindin (R-Y2) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: