Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
NOPE (neighbor of punc E11) is a 1250 amino acid protein that is highly similar to Punc (putative neuronal cell adhesion molecule). Both NOPE and Punc are transmembrane proteins that belong to the immunoglobulin (Ig) superfamily, which includes Deleted in Colorectal Cancer (DCC), a cell surface receptor involved in embryonic development. NOPE contains five fibronectin type-III (FnIII) repeats and four Ig-like C2-type repeats, which suggests a role for NOPE in embryonic differentiation and cell adhesion. Unlike the highly homologous extracellular domains of NOPE and Punc, their cytoplasmic domains are very diverged. NOPE is expressed during embryonic development of the notochord, skeletal muscle, and ventricular zone of the nervous system. NOPE can also be expressed in the hippocampus of the adult brain.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.