Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Neu2 Antibody (37Y) is a high quality monoclonal Neu2 antibody (also designated Neu2 antibody) suitable for the detection of the Neu2 protein of human origin. Neu2 Antibody (37Y) is available as the non-conjugated anti-Neu2 antibody. Neu2 (N-acetyl-alpha-neuraminidase 2), also known as SIAL2 (sialidase 2), is a 380 amino acid cytosolic sialidase that contains two BNR repeats and belongs to the glycosyl hydrolase 33 family. Expressed in fetal liver, skeletal muscle and an embryonic carcinoma cell line, Neu2 functions to catalytically hydrolyze sialyated compounds. More specifically, Neu2 catalyzes the hydrolysis of α-(2,3), α-(2,6) and α-(2,8) glycosidic linkages of terminal sialic acid residues on glycoproteins, glycolipids, oligosaccharides, colominic acid and various synthetic substrates. Neu2 contains an N-linked glycosylation site, an N-terminal F/YRIP sequence motif (common to many sialidase enzymes) and two aspartic acid block consensus sequences. Human Neu2 shares over 72% sequence similarity with its rat and hamster counterparts, suggesting a conserved function between species. Expression of Neu2 in embryonic carcinomas implies a possible role in tumor formation and metastasis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Thank you for your question. This mouse monoclonal antibody has been tested in ELISA and Western blotting applications. Representative data is shown on our website. Please check back for updates!
Answered by: Technical Support
Date published: 2019-04-04
For Western Blot, is it recommended to use denatured or non-denatured conditions with Neu2 (37Y): sc-100570 antibody?
Asked by: jerojero
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.