Nek10 抗体 (97.1): sc-100434

Nek10 Antibody (97.1) is an IgG_2a κ mouse monoclonal Nek10 antibody that detects the Nek10 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Nek10 Antibody (97.1) is available as the non-conjugated anti-Nek10 antibody. NIMA was originally discovered in Aspergillus nidulans as a protein that is necessary for entry into mitosis. Several NIMA-related mammalian proteins have since been identified. Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.

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References:

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