NDUFB3 抗体 (31-B): sc-100564

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB3 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3), also known as B12, is a 98 amino acid hydrophobic protein belonging to the Complex I NDUFB3 subunit family. Ubiquitously expressed, NDUFB3 localizes to the matrix side of the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I.