Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The nuclear Dbf2-related kinases (NDR1 and NDR2) participate in the regulation of cell division and morphology and may be implicated in tumor progression. NDR1 and NDR2 share 86% amino acid identity, but differ in their expression pattern. NDR1 localizes to the nucleus, while NDR2 exhibits punctate cytoplasmic distribution. Also, NDR1 expression appears highest in spleen, lung and thymus, whereas NDR2 shows highest expression in the gastrointestinal tract. However, both NDR1 and NDR2 are regulated by phosphorylation and by the Ca2+-binding protein S-100B. NDR1 and NDR2 may also play a role in the HIV-1 life cycle. Both proteins are cleaved by the HIV-1 protease (PR), which inhibits their enzymatic activity and alters the subcellular localization of NDR2. The genes encoding human NDR1 and NDR2 map to chromosomes 6p21 and 12p11.23, respectively.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.