Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ndn Antibody (36-V) is a high quality monoclonal Ndn antibody (also designated Ndn antibody) suitable for the detection of the Ndn protein of human origin. Ndn Antibody (36-V) is available as the non-conjugated anti-Ndn antibody. Prader-Willi syndrome (PWS) is a neurogenetic disorder resulting from the loss of paternal expression of gene(s) localized in the 15q11-q12 region. Clinical manifestations of this disease include feeding problems in infancy, temper outbursts, perseveration, obsessive-compulsive symptoms and sleep disturbances. Necdin (Ndn) protein is generated from an intronless gene that is located in the Prader-Willi syndrome deletion region. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons. Ndn expression in brain is restricted to post-mitotic neurons and parental alleles display a differential methylation profile in the coding region. Reduced expression of necdin is responsible for at least a subset of the clinical manifestations of PWS including skin picking and improved spatial memory (5,6)..
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-101224: Ndn (36-V) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Randy McDonald
Thank you for your question. Yes, sc-101224: Ndn (36-V) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 4 out of
Produced robust immunoperoxidase membraneProduced robust immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC