Myoneurin 抗体 (JB-17): sc-101082

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- Myoneurin 抗体 JB-17 是小鼠单克隆 IgG_2a κ，Myoneurin抗体, 在1篇文献中引用，规格为100 µg/ml
- 免疫human物种的重组Myoneurin
- 推荐用于 human 来源的Myoneurin WB, IP, IF, IHC(P) 和 ELISA检测
- 关于如何获取Myoneurin (JB-17): sc-101082的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
- 目前，我们还没有完成Myoneurin 抗体 (JB-17)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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Myoneurin Antibody (JB-17) - Western Blotting - Image 34448

Myoneurin Antibody (JB-17) - Immunohistochemistry - Image 36282

Myoneurin Antibody (JB-17) - Immunofluorescence - Image 35789

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Myoneurin Antibody (JB-17) is an IgG_2a κ mouse monoclonal Myoneurin antibody (also designated Myoneurin antibody) suitable for the detection of the Myoneurin protein of human origin by WB, IP, IF, IHC(P) and ELISA. Myoneurin Antibody (JB-17) is available as the non-conjugated anti-Myoneurin antibody. Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Myoneurin, also known as MYNN, OSZF, SBBIZ1 or ZBTB31 (Zinc finger and BTB domain-containing protein 31), is a 610 amino acid protein that belongs to the Krüppel C2H2-type zinc-finger family. Localized to the nucleus and expressed primarily in the neuromuscular system, Myoneurin is thought to be involved in a wide range of developmental events in muscle tissue. Upon nerve injury, Myoneurin expression is dysregulated, suggesting that Myoneurin functions only in normal developmental processes. Myoneurin contains one BTB (POZ) domain and eight CHH2-type zinc fingers through which it may convey DNA-binding activity. Due to alternative splicing events, Myoneurin exists as four isoforms within the cell.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

References:

Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle. | Alliel, PM., et al. 2000. Biochem Biophys Res Commun. 273: 385-91. PMID: 10873615
A molecular epidemiological study of avian paramyxovirus type 1 (Newcastle disease virus) isolates by phylogenetic analysis of a partial nucleotide sequence of the fusion protein gene. | Aldous, EW., et al. 2003. Avian Pathol. 32: 239-56. PMID: 12850913
Neuromuscular expression of the BTB/POZ and zinc finger protein myoneurin. | Cifuentes-Diaz, C., et al. 2004. Muscle Nerve. 29: 59-65. PMID: 14694499
A molecular epidemiological investigation of isolates of the variant avian paramyxovirus type 1 virus (PPMV-1) responsible for the 1978 to present panzootic in pigeons. | Aldous, EW., et al. 2004. Avian Pathol. 33: 258-69. PMID: 15276997
Amplification of MDS1/EVI1 and EVI1, located in the 3q26.2 amplicon, is associated with favorable patient prognosis in ovarian cancer. | Nanjundan, M., et al. 2007. Cancer Res. 67: 3074-84. PMID: 17409414

种属	基因名称	基因ID	染色质位置	亚型（mRNA）即位号码	蛋白质即位号码	OMIM™ 号码
Human	MYNN	Entrez Gene ID: 55892	3q26.2	XM_005247621, XM_005247622, XM_005247624, XM_011512987, XM_017006864, XM_017006865, XM_017006866, XM_017006867, XM_017006868, NM_001185118, NM_001185119, NM_018657	UniProt ID: Q9NPC7	606042

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Protocols Online

针对哺乳动物和非哺乳动物蛋白靶点的单克隆抗体基本上代表了多克隆抗体覆盖的所有靶点。我们提供超过8300种ImmunoCruz^®偶联抗体，从而可以省去使用二抗。

圣克鲁斯生物技术的抗体有超过36万的研究引文。抗Myoneurin抗体(JB-17)在各种科学出版物中有1篇引文。

针对哺乳动物靶标蛋白的一抗，如抗Myoneurin 抗体 (JB-17)，推荐用于检测一系列哺乳动物物种，主要有小鼠，大鼠和人物种。许多哺乳动物抗体也非常适合兽医研究，与羊、猪、羊、猫、犬、牛和马的蛋白靶点反应。圣克鲁斯生物技术的单克隆一抗适用于实验室研究应用，不用于诊断或治疗。

Myoneurin 抗体 (JB-17) Specifications

替代产品名称

Myoneurin

产品克隆名称

JB-17

分类

一抗

Clonality

单克隆抗体

抗体同型

IgG_2a kappa light chain

氨基酸

501-611

抗原表位靶标

Myoneurin

抗原表位种属

human

产品反应性/检测

Myoneurin

种属反应性/检测

human

其它哺乳动物反应性

N/A

其它非哺乳动物反应性

N/A

应用

WB, IP, IF, IHC(P), ELISA

瓶的信息

Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

研究引文

1篇各种科学出版物的引文

可选的偶联物/形式

N/A

针对非哺乳动物靶点的一抗在检测植物、病毒、细菌、鸟类、鱼类、酵母和无脊椎动物的蛋白质方面非常有用。例如果蝇,斑马鱼, 非洲爪蟾蜍, 拟南芥, 秀丽隐杆线虫, 梭菌, 弯曲杆菌, 幽门螺杆菌, 肝炎, HIV, HPV, HSV, 流行性感冒, 克雷白氏杆菌, 结核分支杆菌, 疟原虫, 假单胞菌, RSV, 酿酒酵母, 沙门氏菌, 血吸虫, 志贺氏杆菌 和 葡萄球菌.

圣克鲁斯生物技术单克隆抗体可用于流式细胞术、免疫沉淀、Western blot和免疫染色等分析。抗Myoneurin抗体(JB-17)推荐用于以下应用：WB (Western blotting), IP (Immunoprecipitation), IF (Immunofluorescence), IHC(P) (Immunohistochemistry - Paraffin Embedded), ELISA (Enzyme-Linked Immunosorbent Assay).

我们还有小鼠二抗、对照血清和对照免疫球蛋白，可与我们的单克隆一抗联合使用。

组织提取物，核提取物和全细胞裂解物与圣克鲁斯生物技术单克隆抗体使用，作为western blotting或免疫沉淀阳性对照。核提取物是理想的western blot分析或凝胶移位分析阳性对照。磷酸化富集的全细胞裂解液和组织提取物可用于磷酸化特异性抗体阳性对照。

单克隆二抗有多种偶联形式，包括：Biotin (B), CruzFluor™ 790, 680, 647, 594, 555, and 488, FITC, HRP, PerCP, PerCP-Cy5.5, Texas Red (TR), 和TRITC (tetramethyl rhodamine isothiocyanate) (R)，用于研究应用，像流式细胞术（FCM），免疫荧光（IF），免疫组织化学（IHC）染色和蛋白印迹（WB）。不用于诊断或治疗。

偶联和非偶联的亲和纯化的免疫球蛋白(IgGs)，用于流式细胞术（FCM），免疫荧光（IF），免疫组织化学（IHC），免疫沉淀（IP）和蛋白印迹（WB）应用，作为阴性对照。

正常血清用于免疫组织化学（IHC）应用，作为封闭试剂。所使用的血清应与二抗的种属相匹配。

Can sc-101082: Myoneurin (JB-17) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Professor Griffin

Thank you for your question. Yes, sc-101082: Myoneurin (JB-17) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining

Answered by: Technical Support

Date published: 2017-03-24

Rated 4 out of 5 by JL from Produced clear immunoperoxidase nuclear and Produced clear immunoperoxidase nuclear and cytoplasmic staining in formalin-fixed, paraffin-embedded human placenta tissue. -SCBT QC

Date published: 2015-04-13

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Myoneurin 抗体 (JB-17): sc-101082

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References:

Myoneurin 抗体 (JB-17) Specifications

替代产品名称

产品克隆名称

分类

Clonality

抗体同型

氨基酸

抗原表位靶标

抗原表位种属

产品反应性/检测

种属反应性/检测

其它哺乳动物反应性

其它非哺乳动物反应性

应用

瓶的信息

研究引文

推荐的二抗检测试剂

可选的偶联物/形式

Can sc-101082: Myoneurin (JB-17) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?