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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MVD (mevalonate (diphospho) decarboxylase), also known as MPD (mevalonate pyrophosphate decarboxylase), is a 400 amino acid protein that belongs to the diphosphomevalonate decarboxylase family. Expressed in lung, liver, heart, skeletal muscle, brain, pancreas, placenta and kidney, MVD enzymatically catalyzes the first step in isoprene biosynthesis, namely the ATP-dependent conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate, a cholesterol precursor. MVD exists as a homodimer that simultaneously dehydrates and decarboxylates its substrate while hydrolyzing ATP. As MVD is a crucial enzyme in early cholesterol synthesis, it may be a useful target for drugs that aim to lower serum cholesterol levels.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using MVD (2B5): sc-100559 for immunofluorescence, what dilution of this antibody should I use?
Asked by: Dr Ninau Qelp
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here:
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