Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MTHFD2 (Methylenetetrahydrofolate dehydrogenase 2), also known as NMDMC, is a 350 amino acid bifunctional protein that is responsible for the consecutive interconversion of tetrahydrofolate derivatives which drive the synthesis of purine, methionine and thymidylate. MTHFD2 is bifunctional in that it has methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activity. MTHFD2 requires either NADP or NAD as a cofactor for interconversion. Activity of these cofactors is affected by intracellular magnesium and phosphate concentrations. MTHFD2 functions as a homodimer and is localized to the mitochondria where it is expressed during the development of normal tissue.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100750: MTHFD2 (243.1) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: jerojero
Thank you for your question. Yes, sc-100750: MTHFD2 (243.1) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: