Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Pigmentation is a highly characteristic and distinguishing feature of differentiated melanocytes. Generally speaking, pigmentation decreases with melanoma progression and/or loss of several other differentiated properties of melanocytes. The gene which encodes the MSG1 protein is expressed at high levels in strongly pigmented melanoma cells, but at low levels in weakly pigmented cells, suggesting that MSG1 may be associated with pigmentation. MSG1, also designated CITED1, localizes to the nucleus and only demonstrates expression in melanocytes and testis. The deduced 193 amino acid human MSG1 protein shares 75% sequence homology with mouse MSG1. The MSG1 protein contains a serine/threonine-rich region, and research indicates that a fusion protein containing MSG1 and a DNA-binding domain activates transcription in mammalian cells, the activation of which is dependent upon the acidic domain of MSG1.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.