Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MHC class IIβ Antibody (SW73.2) is a high quality monoclonal MHC class II beta antibody (also designated MHC class II beta antibody, MHC II beta antibody, or MHC 2 beta antibody) suitable for the detection of the MHC class II beta protein of ovine and caprine origin. MHC class IIβ Antibody (SW73.2) is available as the non-conjugated anti-MHC class II beta antibody. Major histocompatibility complex (MHC) molecules, also designated sheep leukocyte antigen (OLA) molecules (HLA orthologs), are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an α and β chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. Human MHC class II molecules bind 13-18 amino acid antigenic peptides. HLA-DM and -DO molecules, which accumulate in endosomal/lysosomal compartments and on the surface of B cells, regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. Distribution of MHC class IIβ in sheep tissue is similar to that found in human. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using MHC class IIβ (SW73.2): sc-101617 for immunofluorescence, what dilution of this antibody should I use?
Asked by: TinTin
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: