Mfn2/Mitofusin 2 抗体 (XX-1): sc-100560

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- Mfn2/Mitofusin 2抗体(XX-1)是小鼠单克隆IgG_2a κ, 在107篇文献中引用，规格为100 µg/ml
- raised against a C-terminus partial recombinant Mfn2 of human origin
- 推荐用于 mouse, rat 和 human 来源的Mitofusin 2 WB, IP, IF, IHC(P) 和 ELISA检测
- 关于如何获取Mfn2/Mitofusin 2 (XX-1): sc-100560的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
- m-IgG Fc BP-HRP and m-IgG_2a BP-HRP 是 Mfn2/Mitofusin 2 Antibody (XX-1) for WB and IHC(P)首选应用二抗。这些试剂现在以套装形式提供Mfn2/Mitofusin 2 Antibody (XX-1) (见下方订购信息).

References:

Control of mitochondrial morphology by a human mitofusin. | Santel, A. and Fuller, MT. 2001. J Cell Sci. 114: 867-74. PMID: 11181170
Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. | Rojo, M., et al. 2002. J Cell Sci. 115: 1663-74. PMID: 11950885
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. | Chen, H., et al. 2003. J Cell Biol. 160: 189-200. PMID: 12527753
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. | Bach, D., et al. 2003. J Biol Chem. 278: 17190-7. PMID: 12598526
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. | Santel, A., et al. 2003. J Cell Sci. 116: 2763-74. PMID: 12759376
Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity. | Ishihara, N., et al. 2004. J Cell Sci. 117: 6535-46. PMID: 15572413

种属	基因名称	基因ID	染色质位置	亚型（mRNA）即位号码	蛋白质即位号码	OMIM™ 号码
Human	MFN2	Entrez Gene ID: 9927	1p36.22	XM_005263543, XM_005263545, XM_005263547, XM_005263548, NM_001127660, NM_014874	UniProt ID: O95140	609260
Mouse	Mfn2	Entrez Gene ID: 170731	4 E2	XM_006538609, XM_006538610, XM_006538611, XM_017320014, NM_001285920, NM_001285921, NM_001285922, NM_001285923, NM_133201	UniProt ID: Q80U63	N/A

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针对哺乳动物和非哺乳动物蛋白靶点的单克隆抗体基本上代表了多克隆抗体覆盖的所有靶点。我们提供超过8300种ImmunoCruz^®偶联抗体，从而可以省去使用二抗。

圣克鲁斯生物技术的抗体有超过36万的研究引文。抗Mfn2/Mitofusin 2抗体(XX-1)在各种科学出版物中有107篇引文。

针对哺乳动物靶标蛋白的一抗，如抗Mfn2/Mitofusin 2 抗体 (XX-1)，推荐用于检测一系列哺乳动物物种，主要有小鼠，大鼠和人物种。许多哺乳动物抗体也非常适合兽医研究，与羊、猪、羊、猫、犬、牛和马的蛋白靶点反应。圣克鲁斯生物技术的单克隆一抗适用于实验室研究应用，不用于诊断或治疗。

Mfn2/Mitofusin 2 抗体 (XX-1) Specifications

替代产品名称

Mitofusin-2

产品克隆名称

XX-1

分类

一抗

Clonality

单克隆抗体

抗体同型

IgG_2a kappa light chain

氨基酸

661-757

抗原表位靶标

Mfn2

抗原表位种属

human

产品反应性/检测

Mitofusin 2

种属反应性/检测

mouse, rat, human

其它哺乳动物反应性

N/A

其它非哺乳动物反应性

N/A

应用

WB, IP, IF, IHC(P), ELISA

瓶的信息

Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

研究引文

107篇各种科学出版物的引文

可选的偶联物/形式

N/A

针对非哺乳动物靶点的一抗在检测植物、病毒、细菌、鸟类、鱼类、酵母和无脊椎动物的蛋白质方面非常有用。例如果蝇,斑马鱼, 非洲爪蟾蜍, 拟南芥, 秀丽隐杆线虫, 梭菌, 弯曲杆菌, 幽门螺杆菌, 肝炎, HIV, HPV, HSV, 流行性感冒, 克雷白氏杆菌, 结核分支杆菌, 疟原虫, 假单胞菌, RSV, 酿酒酵母, 沙门氏菌, 血吸虫, 志贺氏杆菌 和 葡萄球菌.

圣克鲁斯生物技术单克隆抗体可用于流式细胞术、免疫沉淀、Western blot和免疫染色等分析。抗Mfn2/Mitofusin 2抗体(XX-1)推荐用于以下应用：WB (Western blotting), IP (Immunoprecipitation), IF (Immunofluorescence), IHC(P) (Immunohistochemistry - Paraffin Embedded), ELISA (Enzyme-Linked Immunosorbent Assay).

我们还有小鼠二抗、对照血清和对照免疫球蛋白，可与我们的单克隆一抗联合使用。

组织提取物，核提取物和全细胞裂解物与圣克鲁斯生物技术单克隆抗体使用，作为western blotting或免疫沉淀阳性对照。核提取物是理想的western blot分析或凝胶移位分析阳性对照。磷酸化富集的全细胞裂解液和组织提取物可用于磷酸化特异性抗体阳性对照。

单克隆二抗有多种偶联形式，包括：Biotin (B), CruzFluor™ 790, 680, 647, 594, 555, and 488, FITC, HRP, PerCP, PerCP-Cy5.5, Texas Red (TR), 和TRITC (tetramethyl rhodamine isothiocyanate) (R)，用于研究应用，像流式细胞术（FCM），免疫荧光（IF），免疫组织化学（IHC）染色和蛋白印迹（WB）。不用于诊断或治疗。

偶联和非偶联的亲和纯化的免疫球蛋白(IgGs)，用于流式细胞术（FCM），免疫荧光（IF），免疫组织化学（IHC），免疫沉淀（IP）和蛋白印迹（WB）应用，作为阴性对照。

正常血清用于免疫组织化学（IHC）应用，作为封闭试剂。所使用的血清应与二抗的种属相匹配。

優選的 Mfn2/Mitofusin 2 抗體是 Mfn2/Mitofusin 2 抗體 (F-5): sc-515647.

I got only a strong band in 50-60 kDa in mouse brain, it can be the Mfn2 band?

Asked by: rb97

Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.

Answered by: Anonymous

Date published: 2022-02-17

What is the total volume provided of Mfn2 Antibody (XX-1): sc-100560?

Asked by: jenni

This antibody is provided as 100 µg in 1 ml total volume.

Answered by: Technical Support 8

Date published: 2018-04-04

Rated 5 out of 5 by bbqq from 功能很出色用Mfn2/Mitofusin 2抗体 (XX-1)做出来条带很漂亮，背景干净，且比较好显，位置准确

Date published: 2021-08-26

Rated 4 out of 5 by leti89 from Good antibody in WB The antobody works as expected in WB with PC12 whole cell lysates.

Date published: 2021-05-04

Rated 4 out of 5 by laurap230575 from buon anticorpo questo è un buon anticorpo, dà un segnale netto e specifico

Date published: 2020-10-16

Rated 4 out of 5 by arno from bonne fonctionnalité j'ai testé cet anticorps en immunofluorescence sur cellules MCF7 fixées et en western Blot sur lysat cellulaires et fractions enrichies en mitochondries, donne un résultat très satisfaisant

Date published: 2018-02-19

Rated 4 out of 5 by jiali_nie from 还行，杂带比主带还亮我一个月前申请了该样品的试用装，觉得还行，目的条带是有的，但是杂带比主带还亮，总体效果尚可。希望santa的抗体越做越好。

Date published: 2017-09-27

Rated 5 out of 5 by Cweed from A strong and specific antibody. This is a great choice for all you Mfn2 detection needs. It is reactive with mouse, rat, and human in typical lab applications. It will provide clear and specific results with plenty of signal. It has been cited more than 15 times.

Date published: 2016-12-29

Rated 5 out of 5 by fulian from Specific and strong Worked very nicely in Western blot and WB required a antibody dilution of 1:200 to be able to demonstrate the target band in many cancer cell lysates.

Date published: 2016-12-21

Rated 5 out of 5 by SowmyaL from Specific band The specificity of this antibody is really good for WB

Date published: 2016-10-05

Mfn2/Mitofusin 2抗体 (XX-1) Reviews - page 2

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