Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The biosynthesis of fatty acids can occur in the cytoplasm, via the type I fatty acid synthase complex, or in mitochondria, via the type II malonyl-CoA-dependent system. MCAT (mitochondrial malonyl CoA:ACP acyltransferase), also known as MT, MCT (mitochondrial malonyltransferase), fabD or FASN2C, is a member of the type II malonyltransferase family of proteins. Localizing to mitochondria, MCAT is encoded by a nuclear gene and, via an N-terminal localization signal, it is subsequently imported into mitochondria. MCAT functions in lipid metabolism and may be a component of a mitochondrial fatty acid synthase complex. More specifically, MCAT catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein (NDUFAB1), a subunit of respiratory complex 1. This reaction is essential in the initiation of the type II fatty acid biosynthesis system. Two isoforms of MCAT exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100477: MCAT (3B5) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: TinTin
Thank you for your question. Yes, sc-100477: MCAT (3B5) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: