Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAK Antibody (JK-10) is a high quality monoclonal MAK antibody (also designated MAK antibody) suitable for the detection of the MAK protein of human origin. MAK Antibody (JK-10) is available as the non-conjugated anti-MAK antibody. The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. MAK (male germ cell-associated kinase) is a 623 amino acid member of the Ser/Thr protein kinase family. Expressed predominantly in testicular germ cells, MAK contains one protein kinase domain and is believed to play an important role in spermatogenesis, as it is involved in the regulation of cell cycle and cell fate. MAK is a homolog of the S. cerevisiae protein Ime2, a meiosis-specific protein kinase that is required for the initiation of meiosis and spore formation. MAK expression is induced by androgen and MAK physically associates with AR (androgen receptor), functioning as a coactivator. The knockdown of MAK expression results in diminished expression of AR-responsive genes and inhibition of androgen-induced growth.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.