Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAGE-A11 Antibody (YN-2) is a high quality monoclonal MAGE-A11 antibody (also designated MAGE-A11 antibody) suitable for the detection of the MAGE-A11 protein of human origin. MAGE-A11 Antibody (YN-2) is available as the non-conjugated anti-MAGE-A11 antibody. The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-A11 (melanoma antigen family A, 11), also known as MAGE11, MAGE-11, MAGEA-11 or CT1.11 (cancer/testis antigen 1.11), is a 429 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one MAGE domain. Expressed in a variety of tumors, including melanoma, breast cancer and lung cancer, MAGE-A11 functions as an androgen receptor (AR) co-regulator that modulates the interdomain of AR, thereby increasing its activity. Through its regulation of AR, MAGE-A11 is thought to play an important role in embryonic development and tumor progression/transformation. Two isoforms of MAGE-A11 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.