Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ksr-2 Antibody (K75) is an IgG1 κ mouse monoclonal Ksr-2 antibody (also designated Ksr-2 antibody) suitable for the detection of the Ksr-2 protein of mouse, rat and human origin by WB, IP, IF and ELISA. Ksr-2 Antibody (K75) is available as the non-conjugated anti-Ksr-2 antibody. Kinase suppressor of Ras (Ksr) and MAP kinase kinase kinase (MEKK3) are integral members of the MAP kinase pathway. Ksr is a conserved protein that positively regulates Ras signaling and may function as a scaffold for Raf, MEK and ERK. There are two types of Ksr proteins: Ksr-1 and Ksr-2. These two are individually necessary for a few specific Ras-dependent processes, but they are required together for most aspects of Ras-mediated signaling. Ksr-2 plays a key role in Ras-mediated signaling during germline meiotic progression and functions redundantly with Ksr-1 during the development of the excretory system pathway, hermaphrodite vulva, and male spicules. Ksr-2 also functions as a negative regulator of the MEKK3-mediated activation of the MAP kinase pathways (specifically ERK and JNK) and of the NFκB pathways, and it simultaneously inhibits MEKK3-mediated Il-8 production.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can this antibody be used to detect Ksr-2 of canine origin?
Asked by: AbPolly
Thank you for your question. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.