IL-13Rα1 抗体 (GM-1C8): sc-101381

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- IL-13Rα1抗体(GM-1C8)是小鼠单克隆IgG₁ (kappa轻链)，规格为200 µg/ml
- raised against IL-13Rα1 extracellular domain of human origin
- 推荐用于 human 来源的IL-13Rα1 FCM 和 ELISA检测
- 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
- m-IgG Fc BP-HRP 是 IL-13Rα1 Antibody (GM-1C8) for WB and IHC(P) 的首选应用二抗。这个产品以套装形式提供 IL-13Rα1 Antibody (GM-1C8) (参照下方订购信息).

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此外 IL-2/IL-4/IL-7/IL-9/IL-13/IL-15 Receptor Complex 抗体包括 IL-13R α 1, IL-13R α 2, IL-15R α, IL-2R, IL-2R α, IL-2R β, IL-2R γ, IL-4R α, IL-7R 和 IL-9R
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The Th2 cytokine Interleukin-13 (IL-13) plays a critical role in allergen-induced airway hyper-responsiveness (AHR). Two different receptors exist for IL-13, designated IL-13Rα1 (also designated CD213a1) and IL-13Rα2. IL-13Rα1 exists as a heterodimer of IL-13Rα1 and IL-4Rα as a signaling subunit, whereas IL-13Rα2 acts as a decoy receptor for IL-13. Furthermore, TNFα or IL-4 stimulation induces IL-13Rα2 upregulation, while IL-13Rα1 is constitutively expressed. Cell surface localization of IL-13Rα2 abrogates IL-13 signaling, thus IL-13 induced translocation of the receptor from the cytoplasm provides a mechanism for negative-feedback of IL-13 signaling. IL-13Rα1 expression is predominant in B cells, monocytes and T cells, whereas IL-13Rα2 expression is highest in glioma cells.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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優選的 IL-13Rα1 抗體是 IL-13Rα1 抗體 (D-2): sc-398831.

How can IL-13Rα1 (GM-1C8): sc-101381 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Dr Ninau Qelp

In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-101381 PE) or fluoroscein (sc-101381 FITC).

Answered by: Technical Support

Date published: 2017-03-01

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IL-13Rα1 抗体 (GM-1C8): sc-101381

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SEE ALSO...

優選的 IL-13Rα1 抗體是 IL-13Rα1 抗體 (D-2): sc-398831.

How can IL-13Rα1 (GM-1C8): sc-101381 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

IL-13Rα1 抗体 (GM-1C8): sc-101381

QUICK LINKS

SEE ALSO...

優選的 IL-13Rα1 抗體是 IL-13Rα1 抗體 (D-2): sc-398831.

How can IL-13R&alpha;1 (GM-1C8): sc-101381 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

How can IL-13Rα1 (GM-1C8): sc-101381 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?