Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The heat shock response was first described for Drosophila salivary gland cells and morphologically consists of a change in their polytene chromosome puffing patterns that involves de novo synthesis of a few proteins. Similar heat shock proteins were later discovered in bacterial chicken and mammalian cells, and have been subsequently studied in other organisms. A series of proteins, including HSP 90, HSP 70, HSP 20-30 and ubiquitin, are induced by insults such as temperature shock, chemicals and other environmental stress. A major function of HSP 90 and other HSPs is to act as molecular chaperones. HSP 90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound receptor transcriptionally inactive. HSP 90 binds the GR as a heterocomplex composed of either HSP 56 or Cyclophilin D, forming an aporeceptor complex. HSP 90 also exists as a dimer with other proteins such as p60/STI1 and p23, forming an apo-receptor complex with estrogen and androgen receptors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
What is the recommended secondary reagent to be used with this mouse monoclonal primary?
Asked by: AbPolly
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here:
Please contact Technical Service if you have further questions concerning this product.
Rated 4 out of
nice band with clear background1.2500 dilution of primary antibody and 1.5000 dilution of secondary antibody with clean background
Date published: 2017-10-14
Rated 5 out of
Very Versatile AntibodyThis antibody is well-cited for a variety of applications including WB, IP, and IF. Strong, clear signal with little to no background. Detects both constitutive and inducible forms. Works well in a variety of species including mouse, rat, rabbit, and human samples.
Date published: 2017-01-05
Rated 4 out of
We did not have any issues with this monoclonalWe did not have any issues with this monoclonal in our WB.