Thank you for your question. This monoclonal antibody is recommended to specifically detect HMG-2 (also designated HMGB2). However, we have not yet experimentally confirmed that it does not cross-react with HMG-1 (HMGB1).
We do offer an alternative monoclonal antibody, HMG-2 Antibody (D-3): sc-271689, which based on sequence analysis of the a short peptide antigen, is not expected to cross-react with HMG-1.
Date published: 2020-07-14