Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxesShips via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
Hck Antibody (3D12E10) is a high quality monoclonal Hck antibody (also designated HCK Proto-Oncogene antibody, Src Family Tyrosine Kinase antibody, Tyrosine-Protein Kinase HCK antibody, Hematopoietic Cell Kinase antibody, P59-HCK/P60-HCK antibody, P59Hck antibody, P61Hck antibody, or JTK9 antibody) suitable for the detection of the Hck protein of mouse, rat and human origin. Hck Antibody (3D12E10) is available as both the non-conjugated anti-Hck antibody form, as well as multiple conjugated forms of anti-Hck antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Src is the human homolog of the v-src gene of the Rous sarcoma virus, also called avian sarcoma virus or ASV. Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. The human hemopoietic cell kinase (Hck) gene maps to chromosome 20q11-q12 and encodes a 505 amino acid protein. The Hck protein is expressed in hematopoietic cells, and is particularly abundant in granulocytes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
种属 | 基因名称 | 基因ID | 染色质位置 | 亚型(mRNA)即位号码 | 蛋白质即位号码 | OMIM™ 号码 |
---|---|---|---|---|---|---|
Human | HCK | 3055 | 20q11.21 | NM_001172129, NM_001172130, NM_001172131, NM_001172132, NM_001172133, NM_002110 | P08631 | 142370 |
Mouse | Hck | 15162 | 2 H1 | NM_001172117, NM_010407 | P08103 | N/A |