Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
HADHSC (hydroxyacyl-Coenzyme A (CoA) dehydrogenase, short chain), also known as HAD, HHF4, HADH1, SCHAD or M/SCHAD (Medium and short chain L-3-hydroxyacyl-CoA dehydrogenase), is a mitochondrial matrix protein expressed in pancreas, liver, heart, kidney and skeletal muscle. HADHSC exists as a homodimer that participates in lipid metabolism and is essential for the β-oxidation of medium and short chain fatty acids. More specifically, HADHSC catalyzes the dehydrogenation of 3-hydroxyacyl-CoAs to their corresponding 3-ketoacyl-CoAs while NAD+ is simultaneously reduced to NADH. Defects in HADHSC can lead to HADH (3-α-hydroxyacyl-CoA dehydrogenase) deficiency and familial hyperinsulinemic hypoglycemia 4 (HHF4). HADH deficiency is characterized as a metabolic disorder with patients exhibiting hepatoencephalopathy, hypoglycemia, myopathy or cardiomyopathy and sometimes experiencing sudden death. HHF4 is a disorder characterized by elevated insulin secretion that, if left untreated, can cause brain damage from recurrent hypoglycemia episodes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100472: HADHSC (LB-7) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: DefinitelyNotMatt
Thank you for your question. Yes, sc-100472: HADHSC (LB-7) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
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