Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Grancalcin is a calcium-binding protein that is especially abundant in human neutrophils. Grancalcin belongs to the penta EF-hand (PEF) subfamily of EF-hand proteins, which also comprises calpain, sorcin, peflin and ALG-2. Grancalcin forms a homodimer through the association of the unpaired EF5 hands (2-4). Grancalcin undergoes important conformational changes upon binding of calcium, which subsequently exposes hydrophobic amino acid residues to direct the protein to hydrophobic surfaces. Grancalcin interacts with L-plastin, a protein known to have actin bundling activity, which suggests that grancalcin may play a role in the regulation of neutrophil adhesion. Grancalcin is specifically associated with cells originating in the bone marrow, and it is particularly abundant in neutrophils and monocytes, with relatively small amounts detected in lymphocytes (3,5).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.