Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
G protein-coupled receptor 3 (GPR3), also designated ACCA orphan receptor, is a 330 amino acid member of the G protein-coupled receptor 1 family. The function of GPR3 is mediated by G proteins which activate adenylate cyclase. GPR3 is a mutli-pass membrane protein that is located on the cellular membrane of cells and is detected at low levels in the eye, kidney, lung, ovary and testis. GPR3 is most highly expressed in the central nervous system, where it stimulates the production of cAMP, leading to neurite outgrowth and myelin inhibition. In oocytes, this control over cAMP production can halt meiosis and prevent progesterone-induced meiotic maturation. Mice deficient for GPR3 are able to reproduce but have no control over the oocyte maturation process, which results in nondeveloping early embryos and fragmented oocytes as the mice age.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100300: GPR3 (18-L) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Professor Griffin
Thank you for your question. Yes, sc-100300: GPR3 (18-L) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 4 out of
Clear band with good signal when used onClear band with good signal when used on Jurkat whole cell lysate. -SCBT QC
Date published: 2015-04-30
Rated 5 out of
Clean signal obtained in WB on nonClean signal obtained in WB on non-transfected 293T, human GPR3 transfected 293T and Jurkat whole cell lysates with some PTMs causing double band. -SCBT QC
Date published: 2015-03-26
Rated 4 out of
Produced robust immunoperoxidase membraneProduced robust immunoperoxidase membrane staining in formalin-fixed, paraffin-embedded human transitional cell carcinoma tissue. -SCBT QC