Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
GnRHR2 Antibody (67-R) is a high quality monoclonal GnRHR2 antibody (also designated GnRHR2 antibody) suitable for the detection of the GnRHR2 protein of human origin. GnRHR2 Antibody (67-R) is available as the non-conjugated anti-GnRHR2 antibody. Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). GnRHR2 (gonadotropin-releasing hormone (type 2) receptor 2), also known as GnRH-II-R, is a 379 amino acid multi-pass membrane protein that is expressed in a variety of tissues, where it functions as a G protein coupled receptor for GnRH. Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with GnRHR2 (67-R): sc-100301 antibody?
Asked by: cjMara
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Rated 4 out of
Amy D from
Detects 3 bands on WB of porcine testis samplesThis antibody detects 3 nice bands via WB of porcine testis samples. We believe they may correspond to the 7-TM, 6-TM and 5-TM isoforms produced by the pig. We use it at 1:500.
Date published: 2016-12-01
Rated 4 out of
WB publishable data with human androgenWB publishable data with human androgen-dependent LNCaP / androgen-independent DU 145 / PC3 prostate cancer cell lines - SCBT Publication Review
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