Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Gangliosides are key players in determining the nature of tetraspanin interactions and are major components of the tetraspanin web. The GD2 gangliosides are sialic acid-containing glycosphingolipids that play a role in signal transduction and cell-cell recognition. Ganglioside GD2 production is controlled by GM2/GD2 Synthase. It is found in all tissues and localizes to the cell surface. Ganglioside GD2 is involved in the onset of apoptosis by dephos-phorylating focal adhesion kinases. Ganglioside GD2 is abundant on neuroblastoma cells and on all tumors originating in the neuroectoderm, such as malignant melanoma, adult T cell leukemia, and certain colon and gastric cancers. This suggests that Ganglioside GD2 may be a good target for immu-notherapy. Additionally, Ganglioside GD2 is found on mesenchymal stromal cells and may be a unique surface marker.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.