Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
FRG1 is a 258 amino acid nuclear protein encoded by the human gene FRG1. The FRG1 protein is thought to be involved in pre-messenger RNA splicing. FRG1 plays a role in processing pre-rRNA, assembling rRNA into ribosomal subunits and may also be involved in pre-mRNA splicing. Facioscapulohu-meral muscular dystrophy (FSHD) is a disease state associated with internal deletions among the tandem array of D4Z4 repeats on chromosome 4q35, a subtelomere region of chromosome 4 that contains the FRG1 gene. The muscle degeneration that is common in patients with FSHD results from increased expression of genes proximal to the deletion, including FRG1. In addition to muscle degeneration, most FSHD patients also develop abnormalities of the retinal vasculature. FRG1 is expressed in adult and fetal muscle, lymphocytes and placenta. It can be localized to nuclear Cajal bodies or speckles.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using FRG1 (L-07): sc-101050 for immunofluorescence, what dilution of this antibody should I use?
Asked by: AbPolly
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: