Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
FBL18 Antibody (LL-3) is a high quality monoclonal FBL18 antibody (also designated FBL18 antibody) suitable for the detection of the FBL18 protein of human origin. FBL18 Antibody (LL-3) is available as the non-conjugated anti-FBL18 antibody. FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination. FBL18 directly interacts with SKP1A p19 and CUL-1, forming a substrate-recognition component of the SCF-type E3 ubiquitin ligase complex. Four isoforms of FBL18 exist due to alternative splicing.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
what is the target sequence（Immunogen） of sc-100738: FBL18 (LL-3) monoclonal antibody？
Asked by: yunjing
Thank you for your question. FBL18 Antibody (LL-3): sc-100738 was raised against recombinant FBL18 of human origin. No epitope mapping has been performed, so the antibody's exact binding sequence is not known.
Answered by: Tech Support Europe
Date published: 2020-12-08
Can sc-100738: FBL18 (LL-3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: Trav11
Thank you for your question. Yes, sc-100738: FBL18 (LL-3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: