Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
FAAH Antibody (27-Y) is a high quality monoclonal FAAH antibody (also designated FAAH antibody) suitable for the detection of the FAAH protein of mouse, rat and human origin. FAAH Antibody (27-Y) is available as the non-conjugated anti-FAAH antibody. FAAH (fatty acid amide hydrolase) is a membrane-bound enzyme fatty acid amide hydrolase, responsible for the hydrolysis of multiple primary and secondary fatty acid amides, including the neuromodulatory compounds anandamine and oleamide. The degradation of anandamide to arachadonic acid and oleamide to oleic acid, terminates the signaling function of these molecules (2, 3). FAAH degrades amides and esters with equivalent catalytic efficiency, enabling FAAH to function effectively as both an amidase and esterase. FAAH contributes to anandamide uptake by creating and maintaining an inward concentration gradient for anandamide. A natural single nucleotide polymorphism mutation in human FAAH in its homozygous form is strongly associated with problem drug use. This results in a missense mutation (385C-->A) that converts a conserved proline residue to threonine (Pro129-->Thr), producing an FAAH variant that displays normal catalytic properties but enhanced sensitivity to proteolytic degradation. Genetic mutations in FAAH consitute an important risk factor for problem drug use. The human FAAH gene maps to chromosome 1p33.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Hello, we were using sc-26427 and an APC conjugated secondary antibody to detect FAAH by flow. However, sc-26427 was discontinued (we are mid study) and replaced by sc-100739. Can you suggest a replacement secondary APC or supply the original Ab?
Asked by: Rachel Schirer
Thank you for your question. We can offer secondary antibodies conjugated to APC as a special order. Please contact our Technical Service Department to request more detailed information. Please call us toll-free at (800) 457-3801 option 2, or e-mail <[email protected]>.
Unfortunately, we are unable to provide the goat polyclonal antibody, sc-26427. However, we can provide a free 10 µg sample of the recommended replacement mouse monoclonal antibody, FAAH (27-Y): sc-100739. Please contact Technical Service to request a free sample.
Answered by: Technical Support
Date published: 2017-06-22
For Western Blot, is it recommended to use denatured or non-denatured conditions with FAAH (27-Y): sc-100739 antibody?
Asked by: Cweed
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.