Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
EPM2AIP1 Antibody (YS-62) is a high quality monoclonal EPM2AIP1 antibody (also designated EPM2AIP1 antibody) suitable for the detection of the EPM2AIP1 protein of mouse, rat and human origin. EPM2AIP1 Antibody (YS-62) is available as the non-conjugated anti-EPM2AIP1 antibody. EPM2AIP1 (EPM2A interacting protein 1), also known as laforin-interacting protein, is the first recognized Laforin binding partner that may play a critical role in discovering the underlying pathogenesis of Progressive myoclonic epilepsy type 2 (EPM2), also called Lafora disease (LD). EPM2 is an autosomal recessive disease characterized by grand mal seizures and/or myoclonus at about 15 years of age. Rapid and severe mental deterioration follows, often with psychotic features. Survival is less than 10 years after onset. Laforin is the only glycogen phosphatase in mammals that contains a carbohydrate-binding module. Mutations in the glycogen binding domain eliminate the ability of Laforin to dephosphorylate glycogen leading to EPM2 in humans. EPM2AIP1 colocalizes with Laforin to the endoplasmic reticulum. EPM2AIP1 contains two coiled-coil domains and is expressed in heart, brain, placenta, liver, pancreas, kidney and skeletal muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with EPM2AIP1 (YS-62): sc-100651 antibody?
Asked by: cjMara
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.