ENT4 抗体 (SA-18): sc-101295

ENT4 Antibody (SA-18) is an IgG_2a κ mouse monoclonal ENT4 antibody (also designated SLC29A4 antibody or PMAT antibody) suitable for the detection of the ENT4 protein of mouse, rat and human origin by WB, IP and ELISA. ENT4 Antibody (SA-18) is available as the non-conjugated anti-ENT4 antibody. ENT4 (equilibrative nucleoside transporter 4), also known as SLC29A4 (solute carrier family 29 member 4) or PMAT, is a 530 amino acid plasma membrane protein that is involved in the transport of various compounds throughout the body. Highly expressed in skeletal muscle and brain with weaker expression in heart, kidney and liver, ENT4 functions to transport monoamine molecules, such as dopamine and serotonin, to various areas of the brain. ENT4 is thought to catalyze the reuptake of these molecules into presynaptic neurons, thereby regulating neural signaling events. Although the activity of ENT4 is not dependent upon the intracellular concentrations of ions such as calcium and sodium, its activity is thought to be sensitive to changes in membrane potential. Multiple isoforms of ENT4 are expressed due to alternative splicing events.

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References:

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