Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Epstein-Barr virus (EBV) is a human herpesvirus that ubiquitously infects the majority of the human population. Although most EBV infections are asymptomatic, the virus itself is associated with epithelioid and lymphoid malignancies. EBV LMP-2A (Epstein-Barr virus latent membrane protein 2A), also known as LMP2A, is a 497 amino acid EBV protein that exists on the surface of EBV-infected cells and consists of a short C-terminal tail, 12 membrane-spanning domains and a long N-terminal segment. Expressed in most EBV-associated malignancies, EBV LMP-2A associates with protein tyrosine kinases and, via this association, activates the PI 3-kinase (phosphatidylinositol 3-kinase) pathway, thereby preventing apoptosis. Through its ability to regulate PI 3-kinase signaling events, EBV LMP-2A provides growth and developmental survival signals to infected cells, thus facilitating EBV-induced tumorigenesis. Additionally, EBV LMP-2A can mimic B-cell receptor complex (BCR) signaling in BCR-negative cells, further implicating EBV LMP-2A as an important factor in the survival of mutated cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.