DS2 CAS: 374084-31-8
MF: C18H12CIN3OS
MW: 353.83
A positive allosteric modulator of δ-subunit containing GABAA receptors.

DS2 (CAS 374084-31-8)

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Application: DS2 is a positive allosteric modulator of δ-subunit containing GABAA receptors
CAS Number: 374084-31-8
Molecular Weight: 353.83
Molecular Formula: C18H12CIN3OS
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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DS2 a positive allosteric modulator of δ-subunit containing GABAA receptors (EC50 = 142 nM for α4β3δ receptors). Has been shown to display no effects on GABA responses mediated by α4β3γ2 and α1β3γ2 receptors.


参考文献

Wafford et al (2009) Novel compounds selectively enhance d subunit containing GABAA receptors and increase tonic currents in thalamus. Neuropharmacology 56 182.

Physical State :
Solid
Solubility :
DMSO (100mM)
Storage :
Desiccate at 4° C
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
SMILES :
C1=CC2=NC(=C(N2C=C1)NC(=O)C3=CC=C(C=C3)Cl)C4=CC=CS4

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