DS2 (CAS 374084-31-8)
Application:
DS2 is a positive allosteric modulator of δ-subunit containing GABAA receptors
CAS Number:
374084-31-8
Molecular Weight:
353.83
Molecular Formula:
C18H12CIN3OS
仅供科研使用。不可用于诊断或治疗。
DS2 a positive allosteric modulator of δ-subunit containing GABAA receptors (EC50 = 142 nM for α4β3δ receptors). Has been shown to display no effects on GABA responses mediated by α4β3γ2 and α1β3γ2 receptors.
参考文献
Wafford et al (2009) Novel compounds selectively enhance d subunit containing GABAA receptors and increase tonic currents in thalamus. Neuropharmacology 56 182.
Physical State
:
Solid
Solubility
:
DMSO (100mM)
Storage
:
Desiccate at 4° C
Download SDS (MSDS)
Certificate of Analysis
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