Dihydroergotamine Methanesulfonate Salt CAS: 6190-39-2
MF: C33H37N5O5•CH3SO3H
MW: 679.8
A competitive serotonin antagonist and vasoconstrictor.

Dihydroergotamine Methanesulfonate Salt (CAS 6190-39-2)

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Alternate Names: Dihydergot; Dihytamine
Application: Dihydroergotamine Methanesulfonate Salt is a competitive serotonin antagonist and vasoconstrictor
CAS Number: 6190-39-2
Molecular Weight: 679.8
Molecular Formula: C33H37N5O5•CH3SO3H
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Dihydroergotamine Methanesulfonate Salt is a competitive serotonin antagonist and vasoconstrictor.


参考文献

Villalon,C.M.,Born,A.H., denBoer,M.O.,Heiligers,J..P.,Saxena,P.R. "Effects of S9977 and dihydroergotamine in an animal experimental model for migraine." Pharmacol. Res. 25(2), 125 (1992). Doggrell,S.A. "Further analysis of the inhibitory effects of dihydroergotamine, cyproheptadine, and ketanserin on the response of the rat aorta to 5-hydroxytryptamine." J.Auton.Pharmacol. 12(4), 223 (1992). den Boer,M.O.,Heiligers,J.P.,Saxena,P.R. "Carotid vascular effects of ergotamine and dihydroergotamine in the pig: No exclusive mediation via 5-HT1-like receptors." Br.J.Pharmacol. 104(1), 183 (1991).

Appearance :
Powder
Physical State :
Solid
Solubility :
Methanol (21 mg/ml)
Storage :
Store at room temperature
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
SMILES :
C[[email protected]@]1(C(=O)N2[[email protected]](C(=O)N3CCC[[email protected]]3[[email protected]@]2(O1)O)CC4=CC=CC=C4)NC(=O)[[email protected]@H]5C[[email protected]]6[[email protected]@H](CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O

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PMID: # 26385866  Warkus, EL. et al. 2016. Toxicol. Sci. 149: 15-30.

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