DCAKD 抗体 (SQ-14): sc-100348

DCAKD Antibody (SQ-14) is an IgG₁ κ mouse monoclonal DCAKD antibody (also designated DCAKD antibody) suitable for the detection of the DCAKD protein of human origin by WB, IP, IF, IHC(P) and ELISA. DCAKD Antibody (SQ-14) is available as the non-conjugated anti-DCAKD antibody. Coenzyme A (CoA) is an essential cofactor used in numerous biochemical pathways. It plays a critical role in the synthesis and oxidation of fatty acids and is vital to the citric acid cycle. The biosynthesis pathway of CoA from pantothenic acid (also known as vitamin B5) is essential and universal in prokaryotes and eukaryotes. In humans, the final steps of the biosynthesis pathway are carried out by the bifunctional enzyme COASY. The sequence of these enzymes are highly conserved between different bacterial species. The phosphopantetheine adenylyltransferase and dephospho-coenzyme A kinase activities of COASY are evolutionarily conserved activities. DCAKD (dephospho-CoA kinase domain containing protein) is a 231 amino acid protein that consists of a dephospho-CoA kinase domain and an ATP nucleotide binding motif. Localizing to mitochondria and the cytosol, DCAKD belongs to the coaE family which suggests that it may play a role in the biosynthesis of CoA.

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References:

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