D-Serine ethyl ester hydrochloride (CAS 104055-46-1)
Alternate Names:
D-Ser-OEt⋅HCl; D-β-Hydroxyalanine ethyl ester hydrochloride
Application:
D-Serine ethyl ester hydrochloride is a modulator of NMDA receptors
CAS Number:
104055-46-1
Purity:
≥99%
Molecular Weight:
169.61
Molecular Formula:
C5H11NO3·HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
D-Serine ethyl ester hydrochloride has been used to study spinocerebellar ataxia in murine models. It exhibits stereospecific modulation of N-methyl-d-aspartate (NMDA) type glutamate receptors, which appears to reduce ataxia-related falling in a dose-dependent manner.
参考文献
1. Saigoh, K., et al., 1998. The stereo-specific effect of D-serine ethylester and the D-cycloserine in ataxic mutant mice. Brain research. 808(1): 42-7. PMID: 9795125
Physical State
:
Solid
Storage
:
Store at 4° C
Melting Point
:
95-107° C
Refractive Index
:
n20D ~1.46 (Predicted)
Optical Activity
:
α20D +4°±2°, c = 2 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID
:
MDL Number
:
MFCD00191020
SMILES
:
CCOC(=O)[[email protected]@H](CO)N.Cl
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents