Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
COX4I2 Antibody (RR3) is a high quality monoclonal COX4I2 antibody (also designated COX4L2 antibody, or COXIV-2 antibody) suitable for the detection of the COX4I2 protein of human origin. COX4I2 Antibody (RR3) is available as the non-conjugated anti-COX4I2 antibody. The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta. Two isoforms exist for COX4, namely COX4I1 and COX4I2, and they are encoded by two different genes. COX4I2 (Cytochrome c oxidase subunit 4 isoform 2), also known as COX4B, COX4-2, COX4L2 or COXIV-2, is the less common isoform and is incorporated into the COX apoenzyme under hypoxic conditions to optimize COX activity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-100522: COX4I2 (RR3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Asked by: TinTin
Thank you for your question. Yes, sc-100522: COX4I2 (RR3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 3 out of
multiple bandsThis antibody works in WB BUT there are many unspecific signal (1:1000 dilution).
Date published: 2017-12-21
Rated 3 out of
Produced satisfactory immunoperoxidase cytoplasmicProduced satisfactory immunoperoxidase cytoplasmic staining in formalin-fixed, paraffin-embedded human salivary gland tissue. -SCBT QC