Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxesShips via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
COASY (coenzyme A synthase), also known as NBP (nucleotide binding protein), DPCK (dephospho-coenzyme A kinase), PPAT (pantetheine-phosphate adenylyltransferase), UKR1 or pOV-2, is a bifunctional enzyme involved in the biosynthesis of coenzyme A (CoA). COASY exhibits both Ppat activity and DPCK activity, catalyzing steps four and five, respectively, of the CoA biosynthetic pathway. Functioning as a widely expressed monomer and induced by phospholipids, COASY localizes to the outer mitochondrial membrane and facilitates the conversion of 4'-phosphopantetheine to dephospho-CoA and the subsequent generation of CoA. CoA is an important molecule in the cell, participating in carbohydrate, amino acid and fatty acid metabolism. It is the predominant acetyl and acyl group carrier and is used as a substrate by approximately 4% of all cellular enzymes. Due to alternative splicing events, an additional isoform of COASY, namely COASY b, is expressed in brain and contains an extra 29 amino acids at the N-terminus.
种属 | 基因名称 | 基因ID | 染色质位置 | 亚型(mRNA)即位号码 | 蛋白质即位号码 | OMIM™ 号码 |
---|---|---|---|---|---|---|
Human | COASY | 80347 | 17q21.2 | XM_006722116, XM_011525300, XM_017025167, XM_017025168, NM_001042529, NM_001042532, NM_025233, NM_001042530, NM_001042531 | Q13057 | 609855 |