Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CDR2 Antibody (W-12) is a high quality monoclonal CDR2 antibody (also designated CDR2 antibody) suitable for the detection of the CDR2 protein of human origin. CDR2 Antibody (W-12) is available as the non-conjugated anti-CDR2 antibody. CDR2 (cerebellar degeneration-related protein 2), also referred to as Yo or CDR62, is a 545 amino acid protein that is associated with the development of paraneoplastic cerebellar degeneration (PCD). PCD, an immune-mediated syndrome, belongs to a heterogeneous group of rare paraneoplastic neurologic disorders affecting the neurological system. PCD is characterized by subacute cerebellar ataxia and occurs mainly in patients with ovarian, uterine, fallopian tube or breast cancer. Patients with ovarian or breast cancer develop an immune response against cancer cell-expressed CDR2 and Purkinje neuron-expressed CDR2. The presence of the anti-CDR2 antibody in patients with PCD symptoms warrants an aggressive approach to diagnosis and treatment of the underlying cancer.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using CDR2 (W-12): sc-100320 for immunofluorescence, what dilution of this antibody should I use?
Asked by: DefinitelyNotMatt
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here:
Rated 5 out of
this antibody works for my experiment!The molecular wight might a little bit different to the image shown on the website. its about 63kDa in both HFFF and HEK cells. Band was clear in WB, haven't try IF or IP yet.
Date published: 2018-01-18
Rated 5 out of
Beautiful immunofluorescence nuclear stainingBeautiful immunofluorescence nuclear staining in paraformaldehyde-fixed HeLa cells. -SCBT QC