m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for CD67 Antibody (GM2H6) for WB applications. This reagent is now offered in a bundle with CD67 Antibody (GM2H6) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CD67 Antibody (GM2H6) is a high quality monoclonal CD67 antibody (also designated CD67 antibody) suitable for the detection of the CD67 protein of human origin. CD67 Antibody (GM2H6) is available as both the non-conjugated anti-CD67 antibody form, as well as multiple conjugated forms of anti-CD67 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Carcinoembryonic antigen-related cell adhesion molecule 8, also designated CD67, CD66b or nonspecific cross-reacting antigen (NCA-95), belongs to the human carcinoembryonic antigen (CEA) family. The CD67 antigen is encoded by the CEACAM8 (CGM6) gene, which is exclusively expressed in neutrophils and eosinophils. In neutrophils, the CEACAM8 gene is primarily detected in the secondary granules within the cytoplasm, but it can also be found in lower amounts on the plasma membrane. The amount of CD67 on the plasma membrane is up-regulated upon granulocyte activation. CD67 has been located on the surface of neutrophilic and eosinophilic granulocytes at late stages of differentiation. It exhibits heterophilic cell adhesion properties with CD66c, which is coexpressed with CD67 in granulocytes. CD67, which is attached to the membrane by a GPI-anchor, is expressed in leukocytes of chronic myeloid leukemia patients and bone marrow and in granulocytes in the spleen, thymus and lungs.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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