Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CCDC6 Antibody (Q-23) is a high quality monoclonal CCDC6 antibody (also designated TST1 antibody) suitable for the detection of the CCDC6 protein of human origin. CCDC6 Antibody (Q-23) is available as the non-conjugated anti-CCDC6 antibody. CCDC6 (coiled-coil domain containing 6), also known as H4, PTC, TPC or TST1, is a 585 amino acid cytoskeletal protein. Expressed throughout the body, CCDC6 exists in an alpha helical conformation and has a leucine zipper domain through which it can fuse to PDGFR-β (platelet-derived growth factor receptor beta), a protein that functions as a mitogen for mesenchyme- and glia-derived cells. Additionally, CCDC6 is a fusion partner of Ret (RET receptor tyrosine kinase), a proto-oncogene that is involved in GDNF signaling. These fusion products are not present in normal cells, but are the result of a chromosomal rearrangement in the CCDC6 gene which renders the CCDC6 protein susceptible to fusion events. When CCDC6 is fused to either PDGFR-β or Ret, further chromosomal rearrangements may occur that can lead to various carcinomas including human papillary thyroid carcinoma, chronic myelomonocytic leukemia and mammary and cutaneous gland tumors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
For Western Blot, is it recommended to use denatured or non-denatured conditions with CCDC6 (Q-23): sc-100309 antibody?
Asked by: jenni
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.