Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cyclase-associated proteins (CAPs) are a family of evolutionary conserved proteins that participate in signal transduction and function to regulate events associated with the actin cytoskeleton. CAP1 and CAP2 (adenylate cyclase-associated protein 1 and 2, respectively) are two members of the CAP family, both of which localize to the cell membrane and contain one C-CAP/cofactor C-like domain. CAP1 is involved in the regulation of actin filaments and is thought to mediate processes such as establishment of cell polarity and mRNA localization, while CAP2 has a bifunctional regulatory role and can interact directly with actin. Although CAP1 is expressed throughout the body, CAP2 is predominately expressed in skin, brain, heart and skeletal muscle. Overexpression of CAP2 is associated with hepatocellular carcinoma, suggesting a possible role for CAP2 in carcinogenesis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I am using CAP2 (NN12): sc-100916 for immunofluorescence, what dilution of this antibody should I use?
Asked by: AbPolly
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: