(86 21) 6093-6350
C 021 dihydrochloride CAS: 1784252-84-1
MF: C27H41N5O2•2HCl
MW: 540.57
  1. 首页
  2. 化学品
  3. Protein-Interacting Inhibitors, Activators & Substrates
  4. Protein 抑制因子
  5. CKR-4 抑制因子
  6. C 021 dihydrochloride

C 021 dihydrochloride (CAS 1784252-84-1)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 115ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
(0)
写一个评价 提问
Alternate Names: 2-[1,4′-Bipiperidin]-1′-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
CAS Number: 1784252-84-1
Purity: ≥99%
Molecular Weight: 540.57
Molecular Formula: C27H41N5O2•2HCl
仅供科研使用。不可用于诊断或治疗。
Available in US only.
* 参考分析证明 大量特定数据 (包括水 含量).

QUICK LINKS

点击图片或放大按钮来放大

A potent CCR4 chemokine receptor antagonist (IC50 values are 0.14 and 0.039 μM for inhibition of chemotaxis in human and mouse respectively)


参考文献

Yokoyama et al (2009) Potent and orally bioavailable CCR4 antagonists: synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg.Med.Chem. 17 64.

Physical State :
Solid
Solubility :
Soluble in water (50 mM), and DMSO (100 mM).
Storage :
Desiccate at room temperature
IC50 :
CCR4 chemokine receptor: IC50 = 0.14 µM (human); CCR4 chemokine receptor: IC50 = 0.039 µM (mouse); CCL22-binding: IC50 = 73 nM; CCL22-induced GTPγS recruitment: IC50 = 18 nM
仅供科研使用。不可用于诊断或治疗。
Available in US only.
PubChem CID :
56972238
MDL Number :
MFCD16618393
SMILES :
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 99ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

版权所有© 2007-2022 Santa Cruz Biotechnology, Inc. 保留所有权利。

Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。

版权所有© 2007-2022 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。