Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Atrophin interacting proteins (AIP)s bind to atrophin-1 in the vicinity of the polyglutamine tract (1,2). The WW domain consists of 35-40 amino acids and is characterized by four well conserved aromatic residues, two of which are tryptophan (3-6). All five AIPs contain multiple WW domains and can be divided into two distinct classes. AIP1 and AIP3 (WWP3) are MAGUK-like multidomain proteins containing a guanylate kinase-like region, two WW domains, and multiple PDZ domains. AIP2 (WWP2), AIP4 (itchy), and AIP5 (WWP1) are highly homologous, each having four WW domains and a HECT domain characteristic of ubiquitin ligases (1-3). These interactors are similar to isolated huntingtin-interacting proteins, suggesting commonality of function between two families of proteins responsible for similar diseases (1-3).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.