Thank you for your question. According to Uniprot (see below), AATK has 3 isoforms with predicted molecular weights of 145 kDa, 45 kDa and 93 kDa. This antibody would not be able to recognize isoform 2 (missing amino acids 1-433). Based on the observed molecular weights alone, this antibody may recognize both isoform 1 and 3 in the cell lines tested.
Date published: 2019-05-03