(3R)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid is a derivative of azabicycloheptane carboxylic acid, which has been used as a proline replacement in the development of enzyme inhibitors.
1. Venkatraman, Srikanth., et al., 2006. Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid. Bioorganic & medicinal chemistry letters. 16(6): 1628-32. PMID: 16413182
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