Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The survival and development of central neurons require the supply of trophic factors by glial cells. The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, which are glia-derived trophic factors synthesized by 3PGDH. 3PGDH protein is 544 amino acids in length. Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2.1 kb mRNA, which is highly expressed in prostate, testis, ovary, brain, liver, kidney and pancreas, and weakly expressed in thymus, colon and heart, and 710 bp mRNA, which is highly expressed in heart and skeletal muscle. 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status. 3PGDH protein is also highly expressed in adult and fetal brain tissues. 3PGDH protein plays an important role in the metabolism, development and function of the central nervous system and its deficiency is a treatable congential error that impairs L-serine biosynthesis which is characterized by congenital microcephaly, psychomotor retardation and seizures.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is the recommended starting dilution for Western blot for 3PGDH (6B2): sc-100317?
Asked by: jenni
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link:
If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.