Date published: 2025-11-8

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ANKRD18A Inhibidores

ANKRD18A inhibitors represent a specialized class of chemical compounds designed to modulate the activity of the ANKRD18A protein, which is involved in various cellular processes. This protein, characterized by the presence of ankyrin repeat domains, plays a crucial role in protein-protein interactions and the regulation of cellular signaling pathways. ANKRD18A inhibitors typically feature a diverse range of chemical structures, often comprising heterocyclic rings, aromatic systems, and specific functional groups that enhance binding affinity and selectivity for the target protein. The design of these inhibitors focuses on optimizing their interaction with the ANKRD18A protein, often employing techniques such as molecular docking and structure-activity relationship studies to identify optimal chemical scaffolds.

The approaches to creating ANKRD18A inhibitors often involve advanced chemistry methods, including multi-step synthesis and combinatorial chemistry. These inhibitors may exhibit varying degrees of potency and specificity, which are essential for understanding the biological roles of ANKRD18A in cellular contexts. Furthermore, the study of these compounds contributes to the broader understanding of cellular mechanisms by providing tools to dissect the functions of ANKRD18A. Research into this chemical class also involves examining the physicochemical properties of the compounds, such as solubility, stability, and permeability, to ensure their suitability for experimental applications. As a result, ANKRD18A inhibitors serve as valuable resources for researchers investigating the fundamental biology of the ANKRD18A protein and its involvement in various cellular processes.

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Nombre del productoNÚMERO DE CAS #Número de catálogoCantidadPrecioMENCIONESClasificación

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
¥824.00
¥2685.00
¥8089.00
¥28453.00
¥241660.00
53
(3)

Cet antibiotique se lie à l'ADN et inhibe l'ARN polymérase, ce qui peut diminuer la synthèse de l'ARNm de l'ANKRD18A.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
¥451.00
¥925.00
¥2888.00
127
(5)

Este compuesto inhibe la síntesis de proteínas bloqueando la translocación durante la traducción, lo que podría reducir los niveles de proteína ANKRD18A.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
¥699.00
¥1749.00
¥3610.00
233
(4)

Como inhibidor de mTOR, la rapamicina regula a la baja las vías de síntesis de proteínas, lo que podría afectar a la expresión de ANKRD18A.

5-Azacytidine

320-67-2sc-221003
500 mg
¥3159.00
4
(1)

Este análogo de la citidina afecta a la metilación del ADN, lo que podría dar lugar a una expresión alterada de los genes, incluido el ANKRD18A.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
¥1681.00
¥5303.00
¥6995.00
¥13527.00
¥23579.00
33
(3)

Al inhibir las histonas desacetilasas, afecta a la estructura de la cromatina y a la expresión génica, lo que podría repercutir en los niveles de ANKRD18A.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
¥2933.00
¥11609.00
26
(2)

Esta toxina inhibe la ARN polimerasa II, reduciendo potencialmente la transcripción del gen ANKRD18A.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
¥767.00
¥2945.00
8
(1)

Inhibe la inosina monofosfato deshidrogenasa, afectando a la síntesis de nucleótidos y reduciendo potencialmente la síntesis de ARN, incluida la de ANKRD18A.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
¥1094.00
¥2866.00
36
(2)

Este antibiótico inhibe la formación de enlaces peptídicos en los ribosomas, lo que disminuiría la síntesis global de proteínas, incluida la ANKRD18A.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
¥643.00
¥2053.00
¥1038.00
21
(2)

Inhibe la topoisomerasa I del ADN, que es necesaria para la replicación y la transcripción del ADN, afectando potencialmente a la expresión de ANKRD18A.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
¥474.00
¥2087.00
¥3497.00
¥7333.00
6
(1)

Este compuesto inhibe selectivamente la ARN polimerasa II, lo que podría conducir a una disminución de la transcripción del gen ANKRD18A.